Need help? Call us 0800 032 9366
Aspirin linked to greater risk of macular degeneration

Aspirin linked to greater risk of macular degeneration

Thursday 22 October 2020

Aspirin has long been touted as a wonder drug because, in addition to decreasing pain and fever, it has been shown to decrease the risk of heart attacks and strokes in people who are at risk. As a result of this, many people take an aspirin a day, even without having consulted their doctor. New evidence has brought to light that the drug may increase the risk of developing macular degeneration.

Results of a large population study in Taiwan study by the Health Outcome Research Center and the Department of Pharmacy, National Cheng Kung University indicate an increased risk of developing age-related macular degeneration (AMD) in regular aspirin users.

Researchers accessed data from the National Health Insurance Research Database to establish age- and gender-matched cohorts for aspirin and non-aspirin users. Due to over-the-counter medications being covered and tracked by insurance programs in Taiwan, the study was able to access a large amount of data that just isn’t available in many Western countries. Ching-Lan Cheng, PhD and colleagues noted, “The study number is large to present real-world evidence of aspirin use. For a relatively rare disease like AMD, our study provided enough power to discover the low-incidence events and possible association.”

The study population comprised 204,085 individuals using aspirin (100mg per day as dictated by NIH policy) and 478,048 non-users, most in the age range of 45-64 years.

The study calculated that the risk of aspirin users developing AMD was 11.95 per thousand people per year compared to 3.92 per thousand people per year for non-users.

Anyone taking aspirin regularly, or patients who have been prescribed it, should not stop taking it without consulting their doctor first.


  1. HCP Live.
  2. Pub Med.
  3. NHS.



◄ Blog Home

Subscribe to our email newsletter and claim your FREE copy of our popular guide '9 Top Tips to Save Your Sight'


  • Karl Wally
    30 Oct 2020

    What about other blood thinners, such as Plavix?

Post a comment…